There are four subfamilies in the Platystomatidae, to some extent somewhat unstable with changes occurring with regard placement of genera still occasionally happening (McAlpine, 2001). Genera in bold have pages and keys associated with them (click on the link).
Plastotephritinae includes 18 genera:
Agadasys Whittington, 2000
Agrochira Enderlein, 1911
Atopocnema Enderlein, 1922
Cladoderris Bezzi, 1914
Conopariella Enderlein, 1922
Eudasys Whittington, 2003
Federleyella Frey, 1932
Furcamyia Whittington, 2003
Mesanopin Enderlein, 1912
Micronesomyia Whittington, 2003
Oeciotypa Hendel, 1914
Plastotephritis Enderlein, 1922
Prosopoconus Enderlein, 1922
Pterogenomyia Hendel, 1914
Rhegmatosaga Frey, 1930
Stellapteryx Whittington, 2003
Venacalva Whittington, 2003
Xyrogena Whittington, 2003
Platystomatinae includes 80 genera:
Achias Fabricius, 1805
Aetha McAlpine, 2001
Amphicnephes Loew, 1873
Angelopteromyia Korneyev, 2001
Angitula Walker, 1859
Antineura Osten Sacken, 1881
Apactoneura Malloch, 1930
Bama McAlpine, 2001
[Boisduvalia Robineau-Desvoidy, 1830]
Brea Walker, 1859
Bromophila Loew, 1873
Carolimyia Malloch, 1931
Cleitamia Macquart, 1835
Cleitamoides Malloch, 1939
Clitodoca Loew, 1873
Coelocephala Karsch, 1888
Conicipithea Hendel, 1912
Dayomyia McAlpine, 2007
Duomyia Walker, 1849
Elassogaster Bigot, 1860
Engistoneura Loew, 1873
Eosamphicnephes Frey, 1932
Eumeka McAlpine, 2001
Euprosopia Macquart, 1847
Euthyplatystoma Hendel, 1914
Euxestomoea de Meijere, 1913
Himeroessa Loew, 1873
Hysma McAlpine, 2001
Icteracantha Hendel, 1912
Imugana Enderlein, 1937
Inium McAlpine, 1995
Laglaisia Bigot, 1878
Lambia Hendel, 1914
Lamprogaster Macquart, 1843
Lamprophthalma Protschinsky, 1892
Lophoplatystoma Hendel, 1914
Loxoceromyia Hendel, 1914
Loxoneura Macquart, 1835
Loxoneuroides Hendel, 1914
Lulodes Enderlein, 1924
Meringomeria Enderlein, 1924
Metoposparga Enderlein, 1924
Mezona Speiser, 1910
Microepicausta Hendel, 1914
Mindanaia Malloch, 1931
Montrouziera Bigot, 1860
Neoardelio Hendel, 1914
Neoepidesma Hendel, 1914
Oedemachilus Bigot, 1860
Palpomya Robineau-Desvoidy, 1830
Par McAlpine, 2001
Peltacanthina Enderlein, 1912
Peronotrochus Enderlein, 1924
Philocompus Osten Sacken, 1881
Phlebophis Frey, 1932
Phytalmodes Bezzi, 1908
Picrometopus Frey, 1930
Plagiostenopterina Hendel, 1912
Platystoma Meigen, 1803
Pogonortalis Hendel, in de Meijere, 1911
Polystodes Robineau-Desvoidy, 1830
Prosthiochaeta Enderlein, 1924
Pseudepicausta Hendel, 1912
Pseudocleitamia Malloch, 1939
Pseudorichardia Hendel, 1911
Rhytidortalis Hendel, 1914
Rivellia Robineau-Desvoidy, 1830
Scelostenopterina Hendel, 1914
Scotinosoma Loew, 1873
Senopterina Macquart, 1835
Signa McAlpine, 2001
Sors McAlpine, 2007
Sphenoprosopa Loew, 1873
Steyskaliella Soós, 1978
Tarfa McAlpine, 2001
Terzia McAlpine, 2001
Valonia Walker, 1856
Xenaspis Osten Sacken, 1881
Xenaspoides Frey, 1930
Zealandortalis Malloch, 1930
Scholastinae includes 14 genera:
Asyntona Osten Sacken, 1881
Chaetorivellia de Meijere, 1913
Lenophila Guérin-Méneville, 1843
Mesoctenia Enderlein, 1924
Naupoda Osten Sacken, 1881
Neohemigaster Malloch, 1939
Parardelio Hendel, 1912
Paryphodes Speiser, 1911
Pseudoscholastes Frey, 1932
Pterogenia Bigot, 1859
Scholastes Loew, 1873
Tomeus McAlpine, 2001
Trigonosoma Gray, in Griffith & Pidgeon, 1832
Zygaenula Doleschall, 1859
Trapherinae includes 11 genera:
Aglaioptera Frey, 1964
Eopiara Frey, 1964
Lule Speiser, 1910
Phasiamya Walker, 1849
Piara Loew, 1873
Phlyax McAlpine, 2001
Poecilotraphera Hendel, 1914
Seguyopiara Steyskal, 1990
Traphera Loew, 1873
Xiria Walker, 1856
Xiriella Frey, 1964
Unplaced genera (3):
Apiola McAlpine, 1973
Atopognathus Bigot, 1881
Guamomyia Malloch, 1942